Disseminated Bacillus Calmette-Guérin Disease after BCG Vaccination: A Case Report from China

نویسندگان

  • Kun Chen Department of Epidemiology and Biostatistics, Zhejiang University School of Public Health
  • Lin Zheng Institute of Immunization and Prevention, Xihu District Center for Disease Control and Prevention, Hangzhou, China
  • Luoya Ling Institute of Immunization and Prevention, Zhejiang Center for Disease Control and Prevention
  • Mingjuan Jin Department of Epidemiology and Biostatistics, Zhejiang University School of Public Health
  • Shuyun Xie Institute of Immunization and Prevention, Zhejiang Center for Disease Control and Prevention
  • Xiaohua Qi Institute of Immunization and Prevention, Zhejiang Center for Disease Control and Prevention
  • Ye Ding Department of Epidemiology and Biostatistics, Zhejiang University School of Public Health
  • Youqing Wang Department of Epidemiology and Biostatistics, Zhejiang University School of Public Health
چکیده مقاله:

Background: Bacillus Calmette-Guérin (BCG) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. However, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. The disseminated bacillus Calmette–Guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. Case presentation: We report a 4-month-old male infant presenting with recurrent fever, an isolated left axillary massand swelling at the site of BCG inoculation. The cellular immune function analysis showed that the value of CD4/CD8 was 0.994, indicating the existence of immunodeficiency.The results of blood culture and throat swab culture showed conditional pathogen infection. He died of cardiopulmonary failure. Conclusion: In this case, necropsy played a significant role in the final diagnosis of disseminated pulmonary tuberculosis.

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disseminated bacillus calmette-guérin disease after bcg vaccination: a case report from china

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عنوان ژورنال

دوره 12  شماره 1

صفحات  70- 73

تاریخ انتشار 2015-03-01

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